Uniprot MCP
未申請Auditable UniProt MCP server with per-response SHA-256 provenance, release pinning, verification, and offline replay.
01 / クライアントを選択
03 / 設定を追加
claude mcp add --transport stdio 'uniprot-mcp' -- 'uvx' 'uniprot-mcp-server'04 / クライアントで確認
クライアントの MCP 設定で接続とツール一覧を確認してください。設定のコピーだけでは接続成功は確認できません。
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このリスティングは公開情報から自動的にインデックスされました。申請することで、ページの編集、互換性の設定、成長ツールのアンロックができます。2分以内に完了します。
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申請済みおよび認証済みのサーバーは毎週の静的スキャンを受け、コードが到達できる範囲（外部サービス、環境変数、シェルコマンド、エージェント設定フォルダ）と既知のアドバイザリを持つ依存関係が表示されます。このリスティングを申請すると利用できます。 セキュリティプロファイルの仕組み
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ドキュメントに記載されたツール (40)
プロジェクトのドキュメントに基づきます。サーバーのハンドシェイクは、各ツールの説明や動作を検証するものではありません。
uniprot_batch_entries
Up to 100 entries in one call; invalid accessions filtered client-side.
uniprot_compute_properties
Derived sequence chemistry from the FASTA: MW / pI / GRAVY / aromaticity / charge / ε₂₈₀.
uniprot_features_at_position
Every feature overlapping a residue position. Critical for variant-effect interpretation.
uniprot_get_active_sites
Catalytic and ligand-binding residues: active sites, binding sites, sites, metal binding, DNA binding. The residue-level chemistry of the protein.
uniprot_get_alphafold_confidence
alphafold.ebi.ac.uk
uniprot_get_citation
Citation record by ID (typically a PubMed numeric ID).
uniprot_get_cross_refs
Raw cross-references to PDB, Pfam, Ensembl, Reactome, KEGG, STRING …
uniprot_get_disease_associations
Structured disease records from DISEASE-type comments: name + acronym + UniProt disease ID + OMIM cross-ref + description.
uniprot_get_entry
Full UniProt entry (e.g. P04637 for p53). Function, gene, organism, disease, cross-refs.
uniprot_get_evidence_summary
Aggregate ECO codes (Evidence and Conclusion Ontology) across an entry and grade them into a 0-100 evidence-confidence score (high / moderate / low / very-low). Distinguishes wet-lab confirmed from inferred-by-similarity from automatic.
uniprot_get_features
Domains, binding sites, PTMs, signal peptides — optional type filter.
uniprot_get_go_terms
GO annotations grouped by aspect (F / P / C).
uniprot_get_keyword
Keyword by ID (e.g. KW-0007 = Acetylation). Definition, synonyms, GO refs, hierarchy.
uniprot_get_processing_features
Maturation features: signal peptide, propeptide, transit peptide, initiator methionine, chain, peptide. Essential for therapeutic-protein engineering and pathogen-secretion analysis.
uniprot_get_proteome
Proteome by UP ID (UP000005640 = human). Counts, BUSCO score, components.
uniprot_get_ptms
Post-translational modifications: modified residues (phospho/acetyl/methyl), glycosylation, lipidation (GPI/prenyl/palmitoyl), disulfide bonds, cross-links.
uniprot_get_publications
rest.uniprot.org
uniprot_get_sequence
FASTA. PIR-style provenance comment block above the first record (BLAST+ / biopython compatible).
uniprot_get_subcellular_location
Subcellular-location term by ID (e.g. SL-0039 = Cell membrane).
uniprot_get_uniparc
Sequence-archive record by UPI (UPI000002ED67).
uniprot_get_uniref
UniRef cluster by ID (UniRef50P04637, UniRef90P04637, UniRef100P04637).
uniprot_get_variants
Natural variants and disease mutations.
uniprot_id_mapping
Map IDs between databases (GeneName → UniProtKB, PDB → UniProtKB, …).
uniprot_lookup_variant
HGVS-shorthand match (R175H, V600E, R248) against UniProt's natural-variant features.
uniprot_provenance_verify
Re-fetch a previously recorded URL and compare release tag + canonical response SHA-256. Five verdicts (verified, releasedrift, hashdrift, releaseandhashdrift, urlunreachable) each with an advice string.
uniprot_resolve_alphafold
AlphaFold model id + EBI viewer URL (model id only — for pLDDT call the dedicated tool below).
uniprot_resolve_chembl
ChEMBL drug-target id + EBI target-card URL.
uniprot_resolve_clinvar
eutils.ncbi.nlm.nih.gov
uniprot_resolve_interpro
InterPro signatures: id + entry name.
uniprot_resolve_orthology
Group orthology cross-references by source DB (KEGG / OMA / OrthoDB / eggNOG / 8 more).
uniprot_resolve_pdb
PDB structures: id + method + resolution + chain coverage.
uniprot_search
UniProt query language — gene, organism, taxon ID, reviewed flag, free text.
uniprot_search_citations
Index search across UniProt citations.
uniprot_search_keywords
Free-text keyword search.
uniprot_search_proteomes
Filter by organism / type / completeness.
uniprot_search_subcellular_locations
Free-text location search.
uniprot_search_uniparc
UniParc full-text search.
uniprot_search_uniref
Cluster search with identitytier filter (50 / 90 / 100).
uniprot_target_dossier
One-call comprehensive characterisation: nine sections — identity / function / chemistry / structure / drug-target / disease / variants / functional annotations / cross-refs.
uniprot_taxonomy_search
Search UniProt taxonomy by organism name.